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Other antibiotics

Doxycycline

Also sold as: Vibramycin

Prescription neededOther antibiotics
Comes as:CapsuleTablet

Usual adult dose

Usual adult dose: 200 mg on the first day, then 100 mg once or twice a day. Swallow with a full glass of water while sitting or standing, and do not lie down for 30 minutes. Do not take at the same time as milk, antacids or iron.

Your doctor may give you a different dose. Children's doses depend on weight.

Side effects

Common

  • nausea
  • heartburn
  • diarrhoea
  • sunburn more easily

Serious — get help

Stop taking it and see a doctor straight away if you notice:

  • severe headache with blurred vision
  • pain when swallowing (ulcer in the food pipe)
  • severe allergic reaction

Do not take it, or take care, if

  • Pregnancy
  • Breastfeeding
  • Children under 8 (stains teeth), unless a doctor decides it is needed
  • Severe liver disease

Interactions

Medicines that can react with this one.

Serious1 medicineDo not take these together unless your doctor says so.
  • Isotretinoin

    Together they can raise pressure inside the skull (severe headache, vision problems); do not combine.

Pregnancy

  1. A
  2. B
  3. C
  4. D
  5. X

Category D

There is evidence of risk to the baby. Used only in serious situations when safer medicines do not work.

Generic alternatives

Similar medicines your doctor or pharmacist may offer instead.

severe or bloody diarrhoea
Moderate10 medicinesTake together only with care. Ask your doctor or pharmacist.
  • Aluminium hydroxide + Magnesium hydroxide

    Antacids block absorption; leave 2 to 3 hours between them.

  • Calcium carbonate

    Calcium blocks absorption; leave 2 to 3 hours between them.

  • Calcium carbonate + Colecalciferol

    Calcium binds doxycycline in the gut; take them at least 2 to 3 hours apart.

  • Ferrous fumarate

    Iron and doxycycline bind together in the gut; take them at least 2 to 3 hours apart.

  • Ferrous sulfate

    Iron blocks absorption; leave 2 to 3 hours between them.

  • Ferrous sulfate + Folic acid

    Iron and doxycycline bind together in the gut; take them at least 2 to 3 hours apart.

Show 4 more
  • Multivitamin

    Minerals in multivitamins bind doxycycline; take them at least 2 to 3 hours apart.

  • Retinol

    Vitamin A with tetracycline antibiotics can rarely raise pressure in the head (severe headache, blurred vision).

  • Warfarin

    Can raise the effect of warfarin; INR should be checked.

  • Zinc sulfate

    Zinc reduces doxycycline absorption; take them at least 2 hours apart.

Tetracycline
  • Azithromycin
  • Check with my other medicines

    Always follow your doctor or pharmacistThis page is general information, not a prescription. Do not start, stop or change a medicine on your own.