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Emergency and antidotes

Adrenaline

Also sold as: EpiPen

Prescription neededEmergency and antidotes
Comes as:Injection

Usual adult dose

Severe allergic reaction (anaphylaxis): 0.5 mg (0.5 ml of 1 mg/ml) injected into the outer thigh muscle; repeat after 5 minutes if there is no improvement. Children: a smaller dose by weight. Call for emergency help at once.

Your doctor may give you a different dose. Children's doses depend on weight.

Side effects

Common

  • fast heartbeat
  • shaking
  • anxiety
  • pale skin
  • headache

Serious — get help

Stop taking it and see a doctor straight away if you notice:

  • chest pain
  • very irregular heartbeat
  • very high blood pressure
  • stroke

Do not take it, or take care, if

  • In a severe allergic reaction there is no reason not to give it — it can save a life
  • Heart disease, high blood pressure or overactive thyroid (use with caution outside emergencies)

Interactions

Medicines that can react with this one.

Serious1 medicineDo not take these together unless your doctor says so.
  • Propranolol

    Propranolol can block adrenaline and cause a dangerous rise in blood pressure with slow heartbeat.

Moderate1 medicineTake together only with care. Ask your doctor or pharmacist.
  • Amitriptyline

    Amitriptyline can increase the effect of adrenaline on blood pressure and heart rhythm.

Pregnancy

  1. A
  2. B
  3. C
  4. D
  5. X

Category C

A risk to the baby cannot be ruled out. Use only if your doctor says the benefit is greater than the risk.

Check with my other medicines

Always follow your doctor or pharmacistThis page is general information, not a prescription. Do not start, stop or change a medicine on your own.