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Diabetes tablets

Sitagliptin

Also sold as: Januvia

Prescription neededDiabetes tablets
Comes as:Tablet

Usual adult dose

Usual adult dose: 100 mg once a day, with or without food. Lower doses (50 or 25 mg) are used in kidney disease.

Your doctor may give you a different dose. Children's doses depend on weight.

Side effects

Common

  • headache
  • runny or blocked nose
  • sore throat
  • joint pain

Serious — get help

Stop taking it and see a doctor straight away if you notice:

  • severe stomach pain spreading to the back (pancreatitis)
  • severe allergic reaction or blistering skin

Do not take it, or take care, if

  • Type 1 diabetes or diabetic ketoacidosis
  • History of pancreatitis (use with caution)
  • Kidney disease (dose must be reduced)

Interactions

Medicines that can react with this one.

Moderate1 medicineTake together only with care. Ask your doctor or pharmacist.
  • Glimepiride

    The combination increases the risk of low blood sugar; the sulfonylurea dose may need to be lowered.

Minor1 medicineUsually not a problem, but tell your doctor.
  • Digoxin

    Sitagliptin can slightly raise digoxin levels; monitoring may be needed.

Pregnancy

  1. A
  2. B
  3. C
  4. D
  5. X

Category B

No risk seen in animal studies, but there are few studies in pregnant women. Usually considered safe when needed.

Generic alternatives

Similar medicines your doctor or pharmacist may offer instead.

  • Vildagliptin
  • Metformin
  • Empagliflozin
Check with my other medicines

Always follow your doctor or pharmacistThis page is general information, not a prescription. Do not start, stop or change a medicine on your own.