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Cephalosporins

Ceftriaxone

Also sold as: Rocephin

Prescription neededCephalosporins
Comes as:Injection

Usual adult dose

Dose is set by your doctor. Given by injection into a muscle or vein, usually 1 to 2 g once a day. It must not be given in the same drip line as calcium-containing fluids.

Your doctor may give you a different dose. Children's doses depend on weight.

Side effects

Common

  • pain at the injection site
  • diarrhoea
  • mild skin rash

Serious — get help

Stop taking it and see a doctor straight away if you notice:

  • severe allergic reaction (swelling of face or throat
  • difficulty breathing)
  • severe or bloody diarrhoea
  • yellow eyes or skin
  • severe skin rash with blisters

Do not take it, or take care, if

  • Allergy to cephalosporins
  • Severe allergic reaction to penicillin in the past (use with caution)
  • Newborn babies with jaundice, or newborns receiving calcium drips

Interactions

Medicines that can react with this one.

Serious1 medicineDo not take these together unless your doctor says so.
  • Ringer's lactate

    Must not be mixed or given in the same line with calcium-containing fluids; dangerous deposits can form, especially in newborns.

Minor1 medicineUsually not a problem, but tell your doctor.
  • Warfarin

    May raise the effect of warfarin; INR may need checking.

Pregnancy

  1. A
  2. B
  3. C
  4. D
  5. X

Category B

No risk seen in animal studies, but there are few studies in pregnant women. Usually considered safe when needed.

Generic alternatives

Similar medicines your doctor or pharmacist may offer instead.

  • Cefotaxime
  • Cefixime
Check with my other medicines

Always follow your doctor or pharmacistThis page is general information, not a prescription. Do not start, stop or change a medicine on your own.