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ACE inhibitors

Captopril

Also sold as: Capoten

Prescription neededACE inhibitors
Comes as:Tablet

Usual adult dose

Usual adult dose: start 12.5 mg two or three times a day; usual dose 25 to 50 mg two or three times a day. Take about 1 hour before meals.

Your doctor may give you a different dose. Children's doses depend on weight.

Side effects

Common

  • dry cough
  • dizziness
  • taste changes
  • headache

Serious — get help

Stop taking it and see a doctor straight away if you notice:

  • swelling of face
  • lips
  • tongue or throat
  • fainting
  • very high potassium (weakness
  • irregular heartbeat)
  • kidney problems

Do not take it, or take care, if

  • Pregnancy (can harm the baby)
  • Past swelling of face or throat with an ACE inhibitor
  • Narrowing of the arteries to both kidneys
  • Kidney disease or high potassium (use with caution)

Interactions

Medicines that can react with this one.

Serious3 medicinesDo not take these together unless your doctor says so.
  • Lithium carbonate

    ACE inhibitors raise lithium levels and the risk of toxicity.

  • Potassium chloride

    Potassium supplements with ACE inhibitors can cause dangerously high potassium.

  • Spironolactone

    Together they can raise potassium to dangerous levels; blood tests are needed.

Moderate1 medicineTake together only with care. Ask your doctor or pharmacist.
  • Ibuprofen

    NSAIDs reduce the blood pressure effect and raise the risk of kidney damage.

Pregnancy

  1. A
  2. B
  3. C
  4. D
  5. X

Category D

There is evidence of risk to the baby. Used only in serious situations when safer medicines do not work.

Generic alternatives

Similar medicines your doctor or pharmacist may offer instead.

  • Enalapril
  • Lisinopril
  • Ramipril
  • Perindopril
Check with my other medicines

Always follow your doctor or pharmacistThis page is general information, not a prescription. Do not start, stop or change a medicine on your own.