e& Afghanistan
HomeDoctorsAppointmentsHealthProfile
ENدریپښتو
Sign in

e& Afghanistan

See a doctor from your phone — video, voice or chat, in your language.

A digital health service from e& Afghanistan. General health information only — it does not replace a visit to a doctor.

Legal

  • Terms & Conditions
  • Privacy Policy

© 2026 e& Afghanistan. All rights reserved.

  • Home
  • Doctors
  • Appointments
  • Health
  • Profile
Penicillins

Amoxicillin + Clavulanic acid

Also sold as: Augmentin, Calamox

Prescription neededPenicillins
Comes as:TabletSuspensionInjection

Usual adult dose

Usual adult dose: 625 mg (500/125 mg) every 8 hours, or 1 g twice a day, at the start of a meal, usually for 5 to 7 days. Finish the full course. Children: dose by weight — ask your doctor or pharmacist.

Your doctor may give you a different dose. Children's doses depend on weight.

Side effects

Common

  • diarrhoea
  • nausea
  • vomiting
  • mild skin rash
  • vaginal thrush

Serious — get help

Stop taking it and see a doctor straight away if you notice:

  • severe allergic reaction
  • yellow eyes or skin
  • severe or bloody diarrhoea
  • severe skin rash with blisters

Do not take it, or take care, if

  • Allergy to penicillin or any penicillin-type antibiotic
  • Previous jaundice or liver problems with this medicine
  • Severe liver disease
  • Severe kidney disease (dose may need to be lowered)

Interactions

Medicines that can react with this one.

Moderate2 medicinesTake together only with care. Ask your doctor or pharmacist.
  • Methotrexate

    Can reduce methotrexate clearance and raise its toxicity.

  • Warfarin

    Can change the effect of warfarin; INR should be checked during the course.

Pregnancy

  1. A
  2. B
  3. C
  4. D
  5. X

Category B

No risk seen in animal studies, but there are few studies in pregnant women. Usually considered safe when needed.

Generic alternatives

Similar medicines your doctor or pharmacist may offer instead.

  • Amoxicillin
  • Cefuroxime
  • Cefixime
Check with my other medicines

Always follow your doctor or pharmacistThis page is general information, not a prescription. Do not start, stop or change a medicine on your own.