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Asthma and breathing

Aminophylline

Also sold as: Phyllocontin

Prescription neededAsthma and breathing
Comes as:InjectionTablet

Usual adult dose

Dose is set by your doctor. It is mostly given as a slow injection or drip in hospital for severe asthma, with careful monitoring. Slow-release tablets are sometimes used at doses set by the doctor.

Your doctor may give you a different dose. Children's doses depend on weight.

Side effects

Common

  • nausea
  • headache
  • nervousness
  • fast heartbeat
  • trouble sleeping

Serious — get help

Stop taking it and see a doctor straight away if you notice:

  • repeated vomiting
  • fits
  • irregular heartbeat or very low blood pressure (signs of toxic levels)

Do not take it, or take care, if

  • Already taking theophylline (check before an injection is given)
  • Heart rhythm problems, epilepsy or stomach ulcer (use with caution)
  • Liver disease, heart failure or elderly people (dose may need to be lower)

Interactions

Medicines that can react with this one.

Serious1 medicineDo not take these together unless your doctor says so.
  • Ciprofloxacin

    Ciprofloxacin raises theophylline levels and can cause fits and heart rhythm problems.

Moderate2 medicinesTake together only with care. Ask your doctor or pharmacist.
  • Erythromycin

    Erythromycin raises theophylline levels; the dose may need to be reduced.

  • Phenytoin

    Phenytoin lowers theophylline levels, and theophylline can lower phenytoin levels.

Pregnancy

  1. A
  2. B
  3. C
  4. D
  5. X

Category C

A risk to the baby cannot be ruled out. Use only if your doctor says the benefit is greater than the risk.

Generic alternatives

Similar medicines your doctor or pharmacist may offer instead.

  • Theophylline
  • Salbutamol
Check with my other medicines

Always follow your doctor or pharmacistThis page is general information, not a prescription. Do not start, stop or change a medicine on your own.