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Quinolones

Ciprofloxacin

Also sold as: Cipro, Ciproxin

Prescription neededQuinolones
Comes as:TabletDrip (infusion)Eye drops

Usual adult dose

Usual adult dose: 250 to 750 mg twice a day, usually for 3 to 14 days depending on the infection. Drink plenty of water. Do not take at the same time as milk, antacids, iron or zinc — leave at least 2 hours. Finish the full course.

Your doctor may give you a different dose. Children's doses depend on weight.

Side effects

Common

  • nausea
  • diarrhoea
  • headache
  • dizziness
  • trouble sleeping

Serious — get help

Stop taking it and see a doctor straight away if you notice:

  • tendon pain or swelling (especially the heel)
  • numbness or tingling of hands or feet
  • fast or irregular heartbeat
  • seizures
  • severe allergic reaction

Do not take it, or take care, if

  • Children and teenagers who are still growing (unless a doctor decides it is needed)
  • Pregnancy and breastfeeding
  • Previous tendon problems with this type of antibiotic
  • Epilepsy (use with caution)
  • Heart rhythm problems (long QT)
  • Myasthenia gravis

Interactions

Medicines that can react with this one.

Serious4 medicinesDo not take these together unless your doctor says so.
  • Aminophylline

    Ciprofloxacin raises theophylline levels and can cause fits and heart rhythm problems.

  • Sucralfate

    Sucralfate greatly reduces ciprofloxacin absorption; take ciprofloxacin at least 2 hours before.

  • Theophylline

    Raises theophylline levels and can cause seizures or dangerous heart rhythms.

  • Tizanidine

    Ciprofloxacin raises tizanidine levels many times and can cause very low blood pressure and fainting; do not use together.

Moderate10 medicinesTake together only with care. Ask your doctor or pharmacist.
  • Aluminium hydroxide + Magnesium hydroxide

    Antacids block absorption; take ciprofloxacin 2 hours before or 6 hours after.

  • Calcium carbonate

    Calcium reduces absorption of ciprofloxacin; take the antibiotic 2 hours before or 6 hours after calcium.

  • Calcium carbonate + Colecalciferol

    Calcium reduces absorption of ciprofloxacin; take the antibiotic 2 hours before or 6 hours after calcium.

  • Ferrous fumarate

Pregnancy

  1. A
  2. B
  3. C
  4. D
  5. X

Category C

A risk to the baby cannot be ruled out. Use only if your doctor says the benefit is greater than the risk.

Generic alternatives

Similar medicines your doctor or pharmacist may offer instead.

  • Levofloxacin
  • Ofloxacin
Check with my other medicines

Always follow your doctor or pharmacistThis page is general information, not a prescription. Do not start, stop or change a medicine on your own.

Iron reduces absorption of ciprofloxacin; take the antibiotic 2 hours before or 6 hours after iron.

  • Ferrous sulfate

    Iron blocks absorption; take ciprofloxacin 2 hours before or 6 hours after.

  • Ferrous sulfate + Folic acid

    Iron reduces absorption of ciprofloxacin; take the antibiotic 2 hours before or 6 hours after iron.

  • Show 4 more
    • Multivitamin

      Minerals in multivitamins reduce ciprofloxacin absorption; separate by at least 2 to 6 hours.

    • Sodium alginate + Sodium bicarbonate

      Antacid products can reduce ciprofloxacin absorption; take them at least 2 hours apart.

    • Warfarin

      Can raise the effect of warfarin; INR should be checked.

    • Zinc sulfate

      Zinc reduces ciprofloxacin absorption; take ciprofloxacin 2 hours before or 6 hours after.