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Penicillins

Benzylpenicillin

Also sold as: Crystapen

Prescription neededPenicillins
Comes as:Injection

Usual adult dose

Dose is set by your doctor. Given by injection into a vein or muscle in hospital, several times a day, for serious infections such as pneumonia or meningitis.

Your doctor may give you a different dose. Children's doses depend on weight.

Side effects

Common

  • pain at the injection site
  • diarrhoea
  • mild skin rash

Serious — get help

Stop taking it and see a doctor straight away if you notice:

  • severe allergic reaction (swelling of face or throat
  • difficulty breathing)
  • seizures with very high doses

Do not take it, or take care, if

  • Allergy to penicillin or any penicillin-type antibiotic
  • Severe kidney disease (dose must be lowered)
  • Epilepsy (use with caution at high doses)

Interactions

Medicines that can react with this one.

Moderate1 medicineTake together only with care. Ask your doctor or pharmacist.
  • Methotrexate

    Penicillins can reduce methotrexate clearance and raise its toxicity.

Pregnancy

  1. A
  2. B
  3. C
  4. D
  5. X

Category B

No risk seen in animal studies, but there are few studies in pregnant women. Usually considered safe when needed.

Generic alternatives

Similar medicines your doctor or pharmacist may offer instead.

  • Ampicillin
  • Ceftriaxone
Check with my other medicines

Always follow your doctor or pharmacistThis page is general information, not a prescription. Do not start, stop or change a medicine on your own.