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Gout

Colchicine

Also sold as: Colcrys

Prescription neededGout
Comes as:Tablet

Usual adult dose

Usual adult dose for a gout attack: 0.5 mg two to three times a day until the pain settles, as prescribed by your doctor (some doctors give 1 mg at the start, then 0.5 mg an hour later). Do not take more than prescribed — overdose is dangerous.

Your doctor may give you a different dose. Children's doses depend on weight.

Side effects

Common

  • diarrhoea
  • nausea
  • vomiting
  • stomach pain

Serious — get help

Stop taking it and see a doctor straight away if you notice:

  • severe diarrhoea or vomiting
  • muscle pain or weakness
  • numbness
  • unusual bleeding or bruising
  • sore throat with fever

Do not take it, or take care, if

  • Serious kidney or liver disease
  • Taking clarithromycin, erythromycin or other strong interacting medicines
  • Blood disorders
  • Keep out of reach of children — overdose can be fatal

Interactions

Medicines that can react with this one.

Serious2 medicinesDo not take these together unless your doctor says so.
  • Clarithromycin

    Clarithromycin raises colchicine to toxic levels; deaths have been reported.

  • Erythromycin

    Erythromycin raises colchicine levels and the risk of serious toxicity.

Moderate2 medicinesTake together only with care. Ask your doctor or pharmacist.
  • Atorvastatin

    Together they increase the risk of muscle damage; report muscle pain or weakness.

  • Simvastatin

    Together they increase the risk of muscle damage; report muscle pain or weakness.

Pregnancy

  1. A
  2. B
  3. C
  4. D
  5. X

Category C

A risk to the baby cannot be ruled out. Use only if your doctor says the benefit is greater than the risk.

Generic alternatives

Similar medicines your doctor or pharmacist may offer instead.

  • IbuprofenNo prescription needed
  • Naproxen
  • Prednisolone
Check with my other medicines

Always follow your doctor or pharmacistThis page is general information, not a prescription. Do not start, stop or change a medicine on your own.