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Epilepsy and nerve pain

Pregabalin

Also sold as: Lyrica, Gabica

Prescription neededEpilepsy and nerve pain
Comes as:Capsule

Usual adult dose

For nerve pain: start with 75 mg twice a day; the doctor may raise it to 150 mg to 300 mg twice a day. Lower doses are used in kidney disease. It can be misused; do not stop it suddenly.

Your doctor may give you a different dose. Children's doses depend on weight.

Side effects

Common

  • drowsiness
  • dizziness
  • blurred vision
  • unsteady walking
  • swelling of the legs
  • weight gain

Serious — get help

Stop taking it and see a doctor straight away if you notice:

  • slow breathing (especially with opioids)
  • thoughts of suicide

Do not take it, or take care, if

  • Kidney disease (lower dose needed)
  • History of drug misuse (use with caution)
  • Taking opioids or other sedatives (use with caution)
  • Heart failure (use with caution)

Interactions

Medicines that can react with this one.

Serious1 medicineDo not take these together unless your doctor says so.
  • Morphine

    Together they increase sedation and the risk of slowed breathing.

Pregnancy

  1. A
  2. B
  3. C
  4. D
  5. X

Category C

A risk to the baby cannot be ruled out. Use only if your doctor says the benefit is greater than the risk.

Generic alternatives

Similar medicines your doctor or pharmacist may offer instead.

swelling of the face or throat
Moderate3 medicinesTake together only with care. Ask your doctor or pharmacist.
  • Diazepam

    Both cause drowsiness; together they increase sedation and breathing problems.

  • Lorazepam

    Both cause drowsiness; together they increase sedation and falls.

  • Tramadol

    Together they increase drowsiness and dizziness.

Gabapentin
  • Amitriptyline
  • Check with my other medicines

    Always follow your doctor or pharmacistThis page is general information, not a prescription. Do not start, stop or change a medicine on your own.