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Anxiety and sleep (sedatives)

Lorazepam

Also sold as: Ativan

Prescription neededAnxiety and sleep (sedatives)
Comes as:TabletInjection

Usual adult dose

Usual adult dose for anxiety: 1 mg to 4 mg a day in divided doses, for a short time only. The injection is used in hospital, for example to stop a long seizure. Do not stop suddenly after long use.

Your doctor may give you a different dose. Children's doses depend on weight.

Side effects

Common

  • drowsiness
  • tiredness
  • unsteady walking
  • poor memory

Serious — get help

Stop taking it and see a doctor straight away if you notice:

  • slow or shallow breathing
  • severe confusion
  • falls in older people
  • dependence and seizures if stopped suddenly

Do not take it, or take care, if

  • Severe breathing problems or sleep apnoea
  • Severe liver disease
  • Myasthenia gravis
  • Use of alcohol or opioid medicines
  • Pregnancy and breastfeeding
  • Older people (use with caution — risk of falls)

Interactions

Medicines that can react with this one.

Serious2 medicinesDo not take these together unless your doctor says so.
  • Morphine

    Together they can cause deep sedation, slowed breathing and death.

  • Tramadol

Pregnancy

  1. A
  2. B
  3. C
  4. D
  5. X

Category D

There is evidence of risk to the baby. Used only in serious situations when safer medicines do not work.

Generic alternatives

Similar medicines your doctor or pharmacist may offer instead.

Together they can cause deep sedation and slowed breathing.

Moderate2 medicinesTake together only with care. Ask your doctor or pharmacist.
  • Pregabalin

    Both cause drowsiness; together they increase sedation and falls.

  • Sodium valproate

    Valproate raises lorazepam levels; a lower lorazepam dose may be needed.

Diazepam
  • Alprazolam
  • Clonazepam
  • Check with my other medicines

    Always follow your doctor or pharmacistThis page is general information, not a prescription. Do not start, stop or change a medicine on your own.