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Anxiety and sleep (sedatives)

Clonazepam

Also sold as: Rivotril, Clonotril

Prescription neededAnxiety and sleep (sedatives)
Comes as:Tablet

Usual adult dose

Dose is set by your doctor. For panic disorder it is usually 0.25 mg to 1 mg twice a day; for seizures it is started low and raised slowly. Do not stop it suddenly — this can cause seizures.

Your doctor may give you a different dose. Children's doses depend on weight.

Side effects

Common

  • drowsiness
  • tiredness
  • unsteady walking
  • poor memory
  • mood changes

Serious — get help

Stop taking it and see a doctor straight away if you notice:

  • slow or shallow breathing
  • severe confusion
  • thoughts of suicide
  • dependence and seizures if stopped suddenly

Do not take it, or take care, if

  • Severe breathing problems or sleep apnoea
  • Severe liver disease
  • Myasthenia gravis
  • Narrow-angle glaucoma
  • Use of alcohol or opioid medicines
  • Pregnancy and breastfeeding (ask your doctor)

Interactions

Medicines that can react with this one.

Serious2 medicinesDo not take these together unless your doctor says so.
  • Morphine

    Together they can cause deep sedation, slowed breathing and death.

  • Tramadol

    Together they can cause deep sedation and slowed breathing.

Moderate2 medicinesTake together only with care. Ask your doctor or pharmacist.
  • Carbamazepine

    Carbamazepine lowers clonazepam levels.

  • Phenytoin

    Phenytoin lowers clonazepam levels; seizure control should be watched.

Pregnancy

  1. A
  2. B
  3. C
  4. D
  5. X

Category D

There is evidence of risk to the baby. Used only in serious situations when safer medicines do not work.

Generic alternatives

Similar medicines your doctor or pharmacist may offer instead.

  • Diazepam
  • Lorazepam
  • Alprazolam
Check with my other medicines

Always follow your doctor or pharmacistThis page is general information, not a prescription. Do not start, stop or change a medicine on your own.