Glibenclamide
Also sold as: Daonil, Euglucon
Prescription neededDiabetes tablets
Comes as:Tablet
Usual adult dose
Usual adult dose: 2.5 to 5 mg once a day with breakfast, adjusted by your doctor; maximum 15 mg a day. Do not skip meals while taking it.
Your doctor may give you a different dose. Children's doses depend on weight.
Side effects
Common
- low blood sugar (shaking
- sweating
- hunger)
- weight gain
- nausea
Serious — get help
Stop taking it and see a doctor straight away if you notice:
- severe low blood sugar (confusion
- fits
- unconsciousness)
Do not take it, or take care, if
- Type 1 diabetes or diabetic ketoacidosis
- Severe kidney or liver disease
- Elderly people (higher risk of low blood sugar — use with caution)
- Pregnancy and breastfeeding (insulin is usually preferred)
- Allergy to sulfonamide (sulfa) medicines
Interactions
Medicines that can react with this one.
Serious1 medicineDo not take these together unless your doctor says so.
- Fluconazole
Fluconazole raises glibenclamide levels and can cause dangerous low blood sugar.