Fluconazole

Also sold as: Diflucan, Forcan

Prescription neededAntifungals

Comes as:CapsuleTabletSuspensionDrip (infusion)

Antifungals

Fluconazole

Also sold as: Diflucan, Forcan

Prescription neededAntifungals

Comes as:CapsuleTabletSuspensionDrip (infusion)

Usual adult dose

Usual adult dose for vaginal thrush: one 150 mg capsule as a single dose. Other fungal infections: 50 to 400 mg once a day, as prescribed by your doctor.

Your doctor may give you a different dose. Children's doses depend on weight.

Side effects

Common

nausea
stomach pain
headache
diarrhoea
rash

Serious — get help

Stop taking it and see a doctor straight away if you notice:

severe allergic reaction (swelling of face or throat)
yellow eyes or skin
severe skin rash with peeling
fast or irregular heartbeat

Do not take it, or take care, if

Pregnancy (avoid, especially high or repeated doses)
Severe liver disease
Heart rhythm problems (use with caution)
Known allergy to azole antifungals

Interactions

Medicines that can react with this one.

Serious6 medicinesDo not take these together unless your doctor says so.

Amiodarone
Both can prolong the QT interval and cause dangerous heart rhythms.
Glibenclamide
Fluconazole raises glibenclamide levels and can cause dangerous low blood sugar.
Gliclazide
Fluconazole raises gliclazide levels and can cause severe low blood sugar.
Glimepiride
Fluconazole raises glimepiride levels and can cause severe low blood sugar.
Simvastatin
Fluconazole raises simvastatin levels and the risk of muscle damage.
Warfarin
Fluconazole strongly raises the effect of warfarin and the risk of bleeding; INR must be checked.

Moderate2 medicinesTake together only with care. Ask your doctor or pharmacist.

Celecoxib
Fluconazole raises celecoxib levels; a lower celecoxib dose is usually needed.
Phenytoin
Fluconazole raises phenytoin levels; watch for signs of toxicity.