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Antivirals

Daclatasvir

Also sold as: Daklinza, Natdac

Prescription neededAntivirals
Comes as:Tablet

Usual adult dose

Dose is set by your doctor. Usual adult dose: 60 mg once a day together with sofosbuvir, usually for 12 weeks. The dose is changed if you take certain other medicines.

Your doctor may give you a different dose. Children's doses depend on weight.

Side effects

Common

  • headache
  • tiredness
  • nausea

Serious — get help

Stop taking it and see a doctor straight away if you notice:

  • very slow heartbeat (with sofosbuvir and amiodarone)
  • hepatitis B flare in people who also carry hepatitis B

Do not take it, or take care, if

  • Taking rifampicin, carbamazepine or phenytoin
  • Taking amiodarone
  • Pregnancy (ask your doctor)

Interactions

Medicines that can react with this one.

Serious4 medicinesDo not take these together unless your doctor says so.
  • Amiodarone

    With sofosbuvir-based treatment, amiodarone can cause dangerously slow heartbeat.

  • Carbamazepine

    Carbamazepine strongly lowers daclatasvir levels; do not combine.

  • Phenytoin

    Phenytoin strongly lowers daclatasvir levels; do not combine.

  • Rifampicin

    Rifampicin strongly lowers daclatasvir levels; do not combine.

Pregnancy

  1. A
  2. B
  3. C
  4. D
  5. X

Not established

Not established. Ask your doctor before using it in pregnancy or while trying to get pregnant.

Generic alternatives

Similar medicines your doctor or pharmacist may offer instead.

  • Sofosbuvir
Check with my other medicines

Always follow your doctor or pharmacistThis page is general information, not a prescription. Do not start, stop or change a medicine on your own.