Rifampicin
Also sold as: Rifadin
Prescription neededTB medicines
Comes as:Capsule
Also sold as: Rifadin
Dose is set by your doctor as part of TB treatment, usually 10 mg per kg (450 to 600 mg for adults) once a day on an empty stomach. Never stop TB treatment early.
Your doctor may give you a different dose. Children's doses depend on weight.
Stop taking it and see a doctor straight away if you notice:
Medicines that can react with this one.
Rifampicin lowers apixaban levels so it may not prevent clots; avoid.
Rifampicin strongly lowers artemether and lumefantrine levels; treatment may fail.
Rifampicin strongly lowers daclatasvir levels; do not combine.
Rifampicin makes the pill unreliable; use another method of contraception.
Rifampicin lowers itraconazole levels so much that it may not work.
Rifampicin lowers ketoconazole levels so it may not work.
Rifampicin makes emergency levonorgestrel less effective; a double dose or a copper IUD may be advised.
Rifampicin strongly lowers nifedipine levels so blood pressure may not be controlled.
Rifampicin lowers praziquantel levels so much that treatment can fail; stop rifampicin 4 weeks before if possible.
Rifampicin lowers rivaroxaban levels so it may not prevent clots; avoid.
Rifampicin lowers sofosbuvir levels so treatment may fail.
Rifampicin makes dexamethasone work less well.
Rifampicin makes hydrocortisone work less well; replacement doses may need to be increased.
Rifampicin makes methylprednisolone work less well.
Rifampicin lowers norethisterone levels and can make it less effective.
Rifampicin lowers dolutegravir levels; an extra dolutegravir dose is needed.
Rifampicin strongly lowers the effect of warfarin; INR must be checked closely.
Rifampicin lowers steroid levels; a higher steroid dose may be needed.
Rifampicin lowers progesterone levels and can make it less effective.
Rifampicin lowers terbinafine levels and can make it less effective.
Rifampicin lowers theophylline levels and can make it less effective.